ABC-1 is a phosphorylated analogue and a potential antiviral agent against Newcastle disease virus (NDV). ABC-1 has potent antiviral activity.

Product information

CAS Number: 309735-05-5

Molecular Weight: 284.38

Formula: C16H16N2OS

Chemical Name: 6-methoxy-2-{[(4-methylphenyl)methyl]sulfanyl}-1H-1,3-benzodiazole

Smiles: CC1C=CC(CSC2NC3=CC(=CC=C3N=2)OC)=CC=1

InChiKey: HRUYBRGMRSNLNW-UHFFFAOYSA-N

InChi: InChI=1S/C16H16N2OS/c1-11-3-5-12(6-4-11)10-20-16-17-14-8-7-13(19-2)9-15(14)18-16/h3-9H,10H2,1-2H3,(H,17,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ABC-1 (175 and 350 μM; 96 hours) potently inhibits Cytopathic effect (CPE) .

In Vivo:

ABC-1 (2 mg/kg; Oral) reduces colocalized cells in liver and clara cells in lung tissue when compared to NDV control animals.

Products are for research use only. Not for human use.