Cyclophilin B(Loading Control) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65514-50, BS65514-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: P23284

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

Background: The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Cyclophilin B monoclonal Antibody detects endogenous levels of Cyclophilin B protein.

Bioworld Molecular Weight: ~18kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Anti- Cyclophilin B at 1/1000 dilution

Alternative Name: Cphn 2; Cphn2; CyP 20b; CYP S1; CYP-S1; CYPB; MGC14109; MGC2224; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; Peptidyl-prolyl cis-trans isomerase B precursor; Peptidylprolyl isomerase B; PPIase; PPIB; Rotamase; S cyclophilin; SCYLP; PPIB_HUMAN.

Immunogen: Recombinant human Cyclophilin B:C terminus

Conjugate: Unconjugated

Modification: Unmodified