Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.

Product information

CAS Number: 32350-57-5

Molecular Weight: 464.12

Formula: C25H50ClNO4

Chemical Name: [(2R)-3-carboxy-2-(octadecanoyloxy)propyl]trimethylazanium chloride

Smiles: [Cl-].CCCCCCCCCCCCCCCCCC(=O)O[C@H](CC(O)=O)C[N+](C)(C)C

InChiKey: YSVYWVPJJXVIFM-GNAFDRTKSA-N

InChi: InChI=1S/C25H49NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4;/h23H,5-22H2,1-4H3;1H/t23-;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Stearoyl-L-carnitine (0.01-10 μM) inhibits glycine (30 μM) transports by 16.8% at concentrations up 3 μM in Xenopus laevis oocytes. Stearoyl-L-carnitine (500 μM; 30 min) inhibits Na+-dependent [3H]carnitine (20 nM) uptake by ~50% in HPCT cells.

In Vivo:

Stearoyl-L-carnitine is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI) and subjective memory complaint (SMC).

Products are for research use only. Not for human use.